How to Order Prescriptions
VETORYL Capsules are available in 3 sizes (10, 30 and 60 mg) for oral administration based on body weight. Trilostane (4α, 5α-epoxy-17β-hydroxy-3-oxoandrostane-2α-carbonitrile) is an orally active synthetic steroid analogue that selectively inhibits 3 β-hydroxysteroid dehydrogenase in the adrenal cortex, thereby inhibiting the conversion of pregnenolone to progesterone. This inhibition blocks production of glucocorticoids and to a lesser extent, mineralocorticoids and sex hormones while steroid precursor levels increase.
Why Vetoryl Capsules?
- Contain the active ingredient trilostane.
- Trilostane blocks the excessive production of cortisol by reversibly inhibiting the action of the enzyme 3-ß hydroxysteroid dehydrogenase.
- While treatment with trilostane significantly reduces serum cortisol concentrations, it has not been found to reduce aldosterone significantly.†
Adrenocortical suppressant for oral use in dogs only.
Indications
- VETORYL Capsules are indicated for the treatment of pituitary-dependent hyperadrenocorticism in dogs.
- VETORYL Capsules are indicated for the treatment of hyperadrenocorticism due to adrenocortical tumor in dogs.
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